The strength of recommendation is supported by a rating of the quality of the evidence as:
- Very low
- Low
- Moderate
- High.
Each recommendation is supported with information explaining what the intervention is, the rationale for the recommendation, and any associated harms. The intention is to provide sufficient information as to why the recommendation was made to enable a GP to discuss and recommend options for their patient. More information about the GRADE approach can be found within Section 2.4 Formulation of recommendations.