Guideline for the management of knee and hip osteoarthritis

Recommendations

Topical analgesics

Pharmacological interventions

Topical analgesics


 

Intervention: Topical nonsteroidal anti-inflammatory drugs (NSAIDs) – Knee and/or hip

Recommendation

We are unable to recommend either for or against the use of topical NSAIDs for people with knee and/or hip osteoarthritis (OA). It might be reasonable to trial topical NSAIDs for a short period then discontinue use if not effective. Clinicians also need to monitor and capture the adverse effects along with its use.

Strength of recommendation

Conditional (neutral) recommendation

Quality of evidence

Moderate

Intervention: Topical capsaicin – knee and/ or hip

Recommendation

We suggest not offering topical capsaicin for people with knee OA.

Strength of recommendation

Conditional against recommendation 

Quality of evidence

Low

Recommendation

We are unable to recommend either for or against the use of topical capsaicin for people with hip OA.

Strength of recommendation

Conditional (neutral) recommendation

Quality of evidence

Very low

Intervention: Duloxetine – Knee and/or hip

Recommendation

It may be appropriate to offer duloxetine for some people with knee and/or hip OA.

Strength of recommendation

Conditional for recommendation

Quality of evidence

Moderate (knee)
Low (hip

Intervention: Doxycycline – knee and/or hip

Recommendation

We do not recommend offering doxycycline for people with knee and/or hip OA

Strength of recommendation

Strong against recommendation

Quality of evidence

Low (knee)
Very low (hip)

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