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Guideline for the management of knee and hip osteoarthritis

Summary of recommendations

Strong recommendations against the intervention

Guideline for the management of knee and hip osteoarthritis

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Table of contents

Recommendations

Intervention: Oral opioids – Knee and/or hip

Recommendation

We do not recommend offering oral opioids for people with knee and/or hip OA.

Strength of recommendation

Strong against recommendation

Quality of evidence

Low (knee)

Very low (hip)

Refer to full recommendation

Intervention: Transdermal opioids – Knee and/or hip

Recommendation

We do not recommend offering transdermal opioids for people with knee and/or hip OA.

Strength of recommendation

Strong against recommendation

Quality of evidence

Low

Refer to full recommendation

Intervention: Doxycycline – Knee and/or hip

Recommendation

We do not recommend offering doxycycline for people with knee and/or hip OA.

Strength of recommendation

Strong against recommendation

Quality of evidence

Low (knee)
Very low (hip)

Refer to full recommendation

Intervention: Strontium ranelate – Knee and/or hip

Recommendation

We do not recommend offering strontium ranelate for people with knee and/or hip OA.

Strength of recommendation

Strong against recommendation

Quality of evidence

Moderate

Refer to full recommendation

Intervention: IL-1 inhibitors – Knee and/or hip

Recommendation

We do not recommend offering IL-1 inhibitors for people with knee and/or hip OA.

Strength of recommendation

Strong against recommendation

Quality of evidence

Low

Refer to full recommendation

Intervention: FGF – Knee and/or hip

Recommendation

We do not recommend offering FGF for people with knee and/or hip OA.

Strength of recommendation

Strong against recommendation

Quality of evidence

Very low

Refer to full recommendation

Intervention: Viscosupplementation injection – Hip

Recommendation

We do not recommend offering viscosupplementation injection for people with hip OA.

Strength of recommendation

Strong against recommendation

Quality of evidence

Low

Refer to full recommendation

Intervention: Stem cell therapy – Knee and/or hip

Recommendation

We do not recommend offering stem cell therapy for people with knee and/or hip OA.

Strength of recommendation

Strong against recommendation

Quality of evidence

Very low

Refer to full recommendation

Intervention: Arthroscopic, lavage and debridement, meniscectomy and cartilage repair – Knee

Recommendation

We do not recommend offering arthroscopic, lavage and debridement, meniscectomy and cartilage repair for people with knee OA unless the person also has mechanical symptoms of a clinically locked knee as per Australian Knee Society’s ‘Arthroscopy position statement’

Strength of recommendation

Strong against recommendation

Quality of evidence

Very low (lavage and debridement)
Low (meniscectomy)
Very low (cartilage repair)

Refer to full recommendation

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Strong recommendations against the intervention

Recommendations

Intervention: Oral opioids – Knee and/or hip

Recommendation

Strength of recommendation

Quality of evidence

Intervention: Transdermal opioids – Knee and/or hip

Recommendation

Strength of recommendation

Quality of evidence

Intervention: Doxycycline – Knee and/or hip

Recommendation

Strength of recommendation

Quality of evidence

Intervention: Strontium ranelate – Knee and/or hip

Recommendation

Strength of recommendation

Quality of evidence

Intervention: IL-1 inhibitors – Knee and/or hip

Recommendation

Strength of recommendation

Quality of evidence

Intervention: FGF – Knee and/or hip

Recommendation

Strength of recommendation

Quality of evidence

Intervention: Viscosupplementation injection – Hip

Recommendation

Strength of recommendation

Quality of evidence

Intervention: Stem cell therapy – Knee and/or hip

Recommendation

Strength of recommendation

Quality of evidence

Intervention: Arthroscopic, lavage and debridement, meniscectomy and cartilage repair – Knee

Recommendation

Strength of recommendation

Quality of evidence

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