Caring for patients with post–COVID-19 conditions

The most common scenario: Non-specific multisystem post-viral symptoms

The most common scenario: Non-specific multisystem post-viral symptoms

While the specific sequelae of COVID-19 are vast, the majority of patients seeking support from general practice will more than likely experience a range of symptoms, as outlined in Box 2.

Box 2. Post-acute COVID-19 symptoms2,3,12,15
Common symptoms include:
  • fatigue
  • dyspnoea
  • joint pain
  • chest pain
  • cough
  • change in sense of smell or taste
  • cognitive disturbances
  • hoarse voice
 
Less common symptoms include:
  • insomnia
  • low-grade fevers
  • headaches
  • neurocognitive difficulties
  • myalgia and weakness
  • gastrointestinal symptoms
  • rash
  • depression
 

Management of these presentations will usually be pragmatic and symptomatic. Support your patient to maximise their personal wellbeing through diet, exercise and sleep.

Consider and exclude serious complications and possible alternative causes of ongoing symptoms, such as anaemia. Investigate new or worsening symptoms that could indicate delayed sequelae, such as venous thromboembolism (VTE), cardiac complications or pneumonia.

Where possible, optimise the management of the patient’s other chronic conditions.

Identify other social factors that could intersect with their personal health and wellbeing, including smoking, alcohol intake, drug use, risk of mental health issues, risk of family and intimate partner violence, and risk of social isolation. 

Consider current recommendations for management of specific symptoms (refer to Box 3). Management should be guided by the patient’s specific clinical circumstances and be evidence based. Specialist referral should be undertaken, as required.

Box 3. Management of common symptoms
Breathlessness:2,3
  • Optimise management of pre-existing respiratory conditions
  • Recommend respiratory muscle conditioning (pulmonary rehabilitation)
  • Consider chest X-ray at 12 weeks for patients who have had significant respiratory illness
  • Corticosteroids could be considered for inflammatory lung disease on the advice of a respiratory physician
  • Recommend gradual commencement or return to symptom-limited exercise guided by tertiary-trained exercise professionals
  • Referral to a speech pathologist for management of chronic cough, hoarse voice or dysphagia
  • Consider home pulse oximetry measurement
  • Referral to an Accredited Practising Dietitian if symptoms interfere with nutrition, and speech pathology if dysphagia is present
 
Fatigue:2,9,16
  • Maximise self-care, sleep, relaxation and nutrition
  • Recommend that patients pace and be selective when prioritising daily activities
  • Recommend caution with return to exercise (reduce if there is any increase in symptoms)
  • A monitored return to exercise can be supported by an exercise physiology, physiotherapy or rehabilitation referral
  • If fatigue is causing difficulty with activities of daily living (ADLs), recommend energy conservation techniques and home visits by an occupational therapist or rehabilitation service
 
Chest pain:2,9,17
  • Exclude acute coronary syndrome, myocarditis, pericarditis, pulmonary effusion or pulmonary embolism, and arrhythmia
  • Provide education regarding symptoms of concern
  • Patients who have had myocarditis or pericarditis as a component of their acute illness should abstain from vigorous exercise for 3–6 months, and athletes should have cardiology supervision for return to training
  • Refer for graded increase in low-to-moderate activity to increase mobility, exercise capacity and quality of life; this should be facilitated by a physiotherapist or exercise physiologist, or cardiac rehabilitation program
 
Headaches, low-grade fevers and myalgia:2
  • Exclude COVID-19 reinfection or recrudescence
  • Prescribe simple supportive measures and analgesia or antipyretics, as needed
  • Check for secondary infections and prescribe antibiotics, as appropriate
 
Neurocognitive difficulty:2,9
  • Provide supportive management
  • If severe enough to cause difficulty with ADLs, consider cognitive testing, occupational therapy support and speech pathology support for cognitive communication impairment
 
Depression/anxiety:2,18
  • Provide information about post–COVID-19 recovery
  • Use existing standardised screening tools
  • Address multifactorial contributors that might require assistance with pain management, independence with ADLs, financial and other social supports, and loneliness
  • Facilitate access to mental health services or online support if patient is unwilling to access face-to-face counselling
  • Encourage individualised moderate-intensity exercise initiated and supervised by a tertiary-trained exercise professional
  • Refer to an Accredited Practising Dietitian for nutrition support and access to food services
 
Thrombosis risk and contraceptive choice:19
  • COVID-19 causes a hypercoagulable state in some people, which might worsen the VTE risk associated with combined hormonal contraception. The incidence of VTE in biological females of reproductive age with COVID-19 infection is currently not known
  • Patients should be advised of this risk to allow informed choice of contraceptive option
  • For biological females who have had mild or moderate COVID-19 and stopped oral menopausal hormone therapy, also known as hormone replacement therapy, if recommencing, consider using a transdermal preparation
  • For biological females who have had COVID-19 and who are taking oestrogen-containing contraception, manage these medications as per usual care
  • For biological females who have stopped or suspended contraception when they have contracted COVID-19, contraception can be restarted when acute symptoms have resolved
 

Patient collaboration

Collaborate with the patient to develop an individualised management plan to support their recovery. This might also present an opportunity for the development of multidisciplinary models of care guided by the general practice team, using chronic disease management plans, team care plans and case conference items.

It is important to ensure that if you use specific Medicare Benefits Schedule (MBS) items for this (eg Item 721: GP management plan) that you are familiar with and follow the specific item requirements (including descriptors and notes). 

Allied health and other specialist collaboration

Your initial assessment will help inform your management plan. Your patient could benefit from allied health input. Consider collaborating with community and hospital-based allied health, rehabilitation medicine and geriatric medicine services to support individual management planning where appropriate. This might include:

  • physiotherapists
  • exercise physiologists
  • occupational therapists
  • dietitians
  • speech pathologists
  • psychologists
  • occupational and environmental physicians
  • rehabilitation medicine physicians
  • geriatric medicine physicians
  • rehabilitation medicine services including outpatients, day rehabilitation and inpatient rehabilitation
  • geriatric medicine services including outpatients, and geriatric evaluation and management units. 

Multidisciplinary clinics for the management of post–COVID-19 conditions have been established in some jurisdictions. It may be appropriate to refer eligible patients with post–COVID-19 sequalae to these clinics.  Eligibility criteria and referral processes will be defined by each jurisdiction. Check your local Health Pathways or contact your PHN for information on clinics in your area. Alternately your local Health Pathways might have referral pathways for other allied health and specialist clinics. 

Barriers in accessing allied health services might exist for culturally and linguistically diverse (CALD) patients with low English proficiency due to lack of interpreter funding. When referring your patients, ensure the service is able to provide the appropriate care.

  1. World Health Organization. A clinical case definition of post COVID-19 condition by a Delphi consensus, 6 October 2021. Geneva: WHO, 2021 int/publications/i/item/WHO-2019-nCoV-Post_COVID-19_condition-Clinical_ case_definition-2021.1 [Accessed 24 November 2021].
  2. Greenhalgh T, Knight M, A’Court M, Buxton M, Husain L. Management of post- acute covid-19 in primary care. BMJ 2020;370:m3026.
  3. Nalbandian A, Sehgal K, Gupta K, et al. Post-acute COVID-19 syndrome. Nat Med 2021;27(4):601–15.
  4. National Institute for Health and Care Excellence. COVID-19 rapid guideline: Managing the long-term effects of COVID-19. UK: NICE, 2021 [Accessed 6 December 2021].
  5. Pavli A, Theodoridou M, Maltezou H. Post-COVID syndrome: Incidence, clinical spectrum, and challenges for primary healthcare professionals. Arch Med Res 2021;52(6): 575–81.
  6. Office for National Statistics. Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 1 April 2021. UK: Office for National Statistics, 2021 omsfollowingcoronaviruscovid19infectionintheuk/1april2021#measuring-the-data [Accessed 24 November 2021].
  7. Liu B, Jayasundara D, Pye V, et al. Whole of population-based cohort study of recovery time from COVID-19 in New South Wales Australia. Lancet Reg Health West Pac 2021;12:100193.
  8. Antonelli M, Penfold R, Merino J, Sudre C. Risk factors and disease profile of post- vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: A prospective, community-based, nested, case-control study. Lancet Infect Dis 2021;S1473-3099(21)00460-6.
  9. Barker-Davies R, O’Sullivan O, Senaratne K, et al. The Stanford Hall consensus statement for post-COVID 19 rehabilitation. Br J Sports Med 2020;54(16):949–59.
  10. Venkatesan P. NICE guideline on long COVID. Lancet Respir Med 2021;9(2):129.
  11. Australian Institute of Health and Welfare. The first year of COVID-19 in Australia: Direct and indirect health effects. Canberra: Australian Government, 2021 phe-287.pdf [Accessed 23 November 2021].
  12. National COVID-19 Clinical Evidence Taskforce. Care of people with post-COVID-19 (version 4.0). Melbourne: National COVID-19 Clinical Evidence Taskforce, 2022   [Accessed 5 May 2022].
  13. British Society of Rehabilitation Medicine. Rehabilitation in the wake of COVID-19 – A phoenix from the ashes. UK: BSRM, 2020 downloads/covid-19bsrmissue1-published-27-4-2020.pdf  [Accessed 23 November 2021].
  14. Selvaraj V, Dapaah-Afriyie K. Lung cavitation due to COVID 19 pneumonia. BMJ Case  Rep 2020;13(7):e237245.
  15. Carfi A, Bernabei R, Landi R, Gemelli Against COVID-19 Post-Acute Study Group. Persistent symptoms in patients after acute COVID-19. JAMA 2020;324(6):603–05.
  16. Spruit MA, Holland AE, Singh SJ, et al. COVID-19: interim guidance on rehabilitation in the hospital and post-hospital phase from a European Respiratory Society and American Thoracic Society-coordinated international task force. Eur Respir J 2020;56(6):2002197.
  17. Rroku A, Kottwitz J, Heidecker B. Update on myocarditis – what we know so far and where we may be heading. Eur Heart J Acute Cardiovasc Care 2020 (ahead of print).
  18. Firth J, Marx W, Dash S, et al. The effects of dietary improvement on symptoms of depression and anxiety: A meta-analysis of randomized controlled trials. Psychosom Med  2019;81(3):265–80.
  19. National COVID-19 Clinical Evidence Taskforce. Management of adults with mild-COVID-19 (version 42). Melbourne: National COVID-19 Clinical  Evidence Taskforce, 2022  [Accessed 5 May 2022].
  20. National COVID-19 Clinical Evidence Taskforce. Australian guidelines for clinical care of people with COVID-19 (version 56.1) – Venous thromboembolism (VTE) prophylaxis. Melbourne: National COVID-19 Clinical evidence Taskforce, 2022 [Accessed 5 May 2022].
  21. American Society of Haematology. COVID-19 and VTE/anticoagulation: Frequently asked questions (version 12). Washington: American Society of Haematology, 2021 [Accessed 6 December 2021].
  22. Herrera JE, Niehaus WN, Whiteson J, et al. Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fatigue in postacute sequelae of SARS-CoV-2 infection (PASC) patients. PM R 2021;13(9):1027–43.
  23. Thurber K, Barrett E, Agostino J, et al. Risk of severe illness from COVID-19 among Aboriginal and Torres Strait Islander adults: The construct of ‘vulnerable populations’ obscures the root causes of health inequities. Aust N Z J Public Health 2021;4(6):658–63.
  24. Yashashana A, Pollard-Wharton N, Zwi A, Biles B. Indigenous Australians at increased risk of COVID-19 due to existing health and socioeconomic inequities. Lancet Reg Health West Pac 2020;1:100007.
  25. Zimmermann P, Pittet L, Curtis N. How common is long COVID in children and adolescents? Pediatr Infect Dis J 2021;40(12):e482–87.
  26. Murdoch Children’s Research Institute. Frequently asked COVID-19 questions. Melbourne: MCRI, 2021 [Accessed 24 November 2021].
  27. Australian Technical Advisory Group on Immunisation. Clinical guidance  for COVID-19 vaccine providers. Canberra; ATAGI, 2022  [Accessed 5 May 2022].
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