This guide provides evidence-based recommendations, content and statements across key topics constituting best practice in the identification, diagnosis, prevention and treatment of osteoporosis.
Most recommendations in the previous (second) edition were based on critical analysis of published, peer-reviewed evidence from 2006 to 2016, following a systematic review of available evidence. Every section in this new edition has been reviewed and updated with current peer-reviewed evidence by a bone expert with particular subspeciality expertise in that topic. Focused literature searches were also undertaken in subject areas that the Guideline Review Committee felt needed particular attention. These included fracture risk assessment tools, the frequency of dual energy X-ray absorptiometry (DXA) monitoring, patients at ‘imminent’ or ‘very high’ fracture risk and pharmacological therapies. Where there was insufficient evidence available, or where the quality of the evidence did not meet minimum requirements (as described in Appendix A), recommendations were developed through Guideline Review Committee consensus cognisant of the complexities and time constraints of a busy GP. Details on the development process, how to use this guide and membership of the Guideline Review Committee are found in Appendices A, B and D.