Focus

Cancer and the omics revolution

Richard J Epstein, Frank P Lin

Advances in genomic testing

Sarah Donoghue, Lilian Downie, Chloe Stutterd

Immunotherapy of cancer

Joseph A Trapani, Phillip K Darcy

The gut microbiome

Mayenaaz Sidhu, David van der Poorten

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Up front

Editorial: Paradigm shifts

Sophia Samuel

Letters to the editor

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Clinical

A synopsis of current international guidelines and new modalities for the treatment of varicose veins

Nicholas Kemp

Conservation surgery and radiation therapy in early breast cancer – An update

Ellen Tailby, John Boyages AM

A sugary problem

Emma Foster, Phoebe Gao, Jorge Zavala

Mucocutaneous lesions and nail pigmentation in a patient with essential thrombocytosis

Alba Calleja Algarra, Raquel Aragón Miguel, Fátima Tous Romero, Lidia Maroñas Jiménez

A painful papule on the ear

Thomas J Stewart

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Research

Esperance pica study

Kuroush A Ardeshirian, Donald A Howarth

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Professional

How can GPs drive software changes to improve healthcare for Aboriginal and Torres Strait Islanders peoples?

Helen Kehoe

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Unknown

A survey of hepatitis C management by Victorian GPs after PBS-listing of direct-acting antiviral therapy

Amanda Wade, Bridget Draper, Joseph Doyle, Nicole Allard, Paul Grinzi, Alexander Thompson, Margaret Hellard

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Back pages

Clinical challenge