Australian Family Physician
Australian Family Physician


Volume 40, Issue 10, October 2011

Fixed dose combination diabetes medicines Usage in the Australian veteran population

Malcolm Gillies Yeqin Zuo Svetla Gadzhanova Elizabeth Roughead
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To examine initiation and prescribing patterns of metformin-glibenclamide and metformin-rosiglitazone fixed dose combination products within the Australian veteran population.
A minority of veterans started taking the combination products after being stabilised on the individual products; many had no prior history of oral hypoglycaemic use. This prescribing may lead to wastage if combination medications are poorly tolerated or, more importantly, may cause adverse events.
Of metformin-glibenclamide initiations, 9% involved a switch from metformin and glibenclamide as separate products, while 22% had used neither metformin nor a sulfonylurea. Thirty percent of metformin-rosiglitazone initiations involved a switch from both individual products, while in 10% neither metformin nor thiazolidinedione had been dispensed.

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