Background Yellow fever is a mosquito borne flaviviral haemorrhagic fever endemic to parts of Africa
and South America. One in seven patients develop severe, frequently fatal disease
characterised by multi-organ involvement.
Objective This article outlines the clinical features, epidemiology, prevention and vaccine
recommendations for yellow fever in order to assist the general practitioner when
providing travel medicine advice to patients.
Discussion Travellers are at risk of yellow fever in endemic areas, especially in forested and rural
regions and during urban outbreaks. In addition to antimosquito measures, it is
important to prevent yellow fever by vaccinating where there is true risk, or where it is
required by international health regulations. However, the vaccine is associated with rare
but severe adverse reactions and the need for vaccination should be carefully evaluated.
Download the PDF for the full article.
Download article PDF