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Generating revenue of over $1 billion annually to owner companies, blockbuster drugs have been a prominent feature of drug development over recent decades. However, a large number of patients have an inadequate therapeutic response to the ‘one size fits all’ blockbuster drugs. It is difficult...

Malnutrition is broadly defined as a nutritional deficit (undernutrition), excess (overnutrition) or imbalance.1,2 Malnutrition and unintentional weight loss are issues frequently underestimated in older people that can be limited, managed and controlled by timely nutrition intervention.

Mental illness is common among women of childbearing age, and fertility rates of women with mental illness are close to those of the general population. General practitioners will see most of the women who may be seeking advice and management of their mental illnesses before, during or after...

Persistent pelvic pain (PPP) can be defined as pain in the area of the pelvis that has been present on most days for more than 6 months.1 No statistical data for the prevalence of PPP in Australia are available, but estimates of community prevalence in women range from 15% (USA)2 to 25.4% (New...

The common cold contributes to a high burden of disease in the general population despite its minor and temporary effect.1 The high prevalence and notable impact on quality of life with the common cold generates an economic burden greater than any other clinical condition.2 The common cold is...

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Guidelines and systematic reviewsThank you for the article by van Driel and Spurling (AFP June 2017),1 which stresses the need to apply as much caution to assessing a guideline as is applied to a clinical paper. The article stresses the risks of selection biases:Publication bias – were only the...

BackgroundIn common with many countries, the training of medical graduates for entry into general practice in Australia uses an apprenticeship model of experiential learning in accredited teaching practices (TPs). The content of the experience is an important factor in ensuring that trainees are...

CaseA man, 28 years of age, presented to an emergency department with a seven-day history of lethargy, which he attributed to the recent stress of working on a university thesis. The day before, he developed what he described as mouth ulcers, which progressively became more painful, causing some...

CaseA woman aged 88 years was hospitalised with a community-acquired pneumonia and started empirical treatment with amoxicillin/clavulanic acid and azithromycin. Three days later, she developed a pruritic skin eruption consisting of non-follicular pustules on a widespread oedematous erythema. The...