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This boxed set was made somewhere about 1880 and lacks the bulb that would have been in the empty oval in the box. The nozzles are made from vulcanite, a very hard form of rubber that was first made in the 1850s. The original bulb would have been made from red rubber which, unfortunately, is a material that perishes easily. This is not a syringe of the type that we know. The various nozzles would screw into the bulb and would have served a number of different purposes. Syringes of this type were available at least until the1950s and were used for enemas and to syringe ears.