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Guideline

Pharmacologic approaches to prevention and treatment

Pharmacologic approaches to prevention and treatment

Pharmacological approaches to prevention and treatment may be divided as follows:
  • antiresorptive therapy (inhibits osteoclast activity)
    • bisphosphonates (eg alendronate, risedronate, zoledronate/zoledronic acid)
    • denosumab
    • menopausal hormone therapy (eg oestrogen, tibolone)
    • selective oestrogen receptor modulators (SERMs; eg raloxifene)
  • osteoanabolic therapy (predominant stimulatory effect on osteoblasts)
    • teriparatide
    • romosozumab (also inhibits osteoclast activity).

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