Breast cancer
| Age | 0 - 9 | 10 - 14 | 15 - 19 | 20 - 24 | 25 - 29 | 30 - 34 | 35 - 39 | 40 - 44 | 45 - 49 | 50 - 54 | 55 - 59 | 60 - 64 | 65 - 69 | 70 - 79 | >80 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| X | X | X | X |
For women at average risk and aged 50–69 years, screening by mammogram every 2 years is recommended (A). For women who are eligible and attending for regular mammographic screening, there is no evidence that clinical breast examination will provide additional benefit (E). Mammographic screening is not recommended for women at average risk under 40 years of age. All women should be advised to be familiar with the normal look and feel of their breasts and to report any new or unusual changes to their GP without delay. No specific technique is promoted for breast self examination as there is no evidence of the effectiveness of any one approach. The breast awareness approach should be seen as a supplement to, not a substitute for, regular mammograms in women within the target age range for screening.390
| Who is at higher risk of breast cancer? | What should be done? | How often? | Level of evidence and references |
|---|---|---|---|
Average risk or slightly above (>95% of the female population)
As a group, lifetime risk of breast cancer is between one in 11 and one in 8. This risk is no more than 1.5 times the population average |
|
Every 2 years from 50-69 years of age* Regular |
I A 391-396 |
Moderately increased risk (<4% of the female population)
As a group, lifetime risk of breast cancer is between one in 8 and one in 4. | Mammogram Breast awareness Consider referral to, or consultation with, a family cancer clinic for further assessment |
At least every 2 years from 50-69 years of age* |
III C 391 |
Potentially high risk (<1% of the female population)
Women in high risk groups may carry BRCA1 or BRCA2 or other gene mutations. Women who carry BRCA1 and BRCA2 mutations are at high risk of developing breast cancer and ovarian cancer See the National Breast Cancer Centre (NBCC) guidelines. Available at www.nbcc.org.au for further information As a group, lifetime risk of breast cancer is between one in 4 and one in 2. Risk may be more than three times the population average. Individual risk may be higher or lower if genetic test results are known | Advise referral to a cancer specialist or family cancer clinic for development of an individualised surveillance program This may include clinical breast examination, mammography and/ or ultrasound and surveillance for ovarian cancer |
Individualised surveillance program |
III C 391 |
| For all women there is a chance that mammography will either miss a change due to breast cancer (false negative) or that further tests will be performed to examine a change that is not due to breast cancer (false positive). The chance of a false negative or false positive result is higher in younger women because their breast tissue is more dense. Women 40–49 years of age should be advised that the benefits of mammographic screening increase with increasing age. Women in this age group are more likely to be recalled for additional assessment and investigation.392,393 Women in this age group should balance the benefits and downsides of mammographic screening for them. Breast cancer remains common and can be readily detected by mammography in women over 70 years of age. With increasing life expectancy some women may elect to continue regular mammographic screening to an age decided in consultation with their doctor having regard to comorbidities and life expectancy394 | |||
A recent systematic review of strategies for increasing the participation of women in community breast cancer screening found five active strategies for inviting women into community breast cancer screening services to be favourable: letter of invitation, mailed educational material, letter of invitation plus phone call, phone call, and training activities plus direct reminders.401 Physical activity is associated with a reduced risk of breast cancer.397 Studies have shown a 20–40% reduction in risk of breast cancer in both pre- and post-menopausal women.398
© The Royal Australian College of General Practitioners
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